Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | transDMpreB |
| GeneSet | HUMANCYC_SUPERPATHWAY OF HISTIDINE, PURINE, AND PYRIMIDINE BIOSYNTHESIS |
| Enrichment Score (ES) | 0.8141957 |
| Normalized Enrichment Score (NES) | 1.6624422 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.009981839 |
| FWER p-Value | 0.162 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NME2 | 9468 | 49 | 8.321 | 0.0608 | Yes | ||
| 2 | CTPS | 2514 15772 | 50 | 8.280 | 0.1239 | Yes | ||
| 3 | NME1 | 9467 | 68 | 7.855 | 0.1829 | Yes | ||
| 4 | IMPDH2 | 10730 | 69 | 7.844 | 0.2427 | Yes | ||
| 5 | CAD | 16886 | 71 | 7.817 | 0.3022 | Yes | ||
| 6 | PPAT | 6081 | 93 | 7.493 | 0.3582 | Yes | ||
| 7 | UMPS | 22606 1760 | 120 | 7.024 | 0.4104 | Yes | ||
| 8 | ATIC | 14231 3968 | 130 | 6.917 | 0.4626 | Yes | ||
| 9 | NME4 | 23065 1577 | 165 | 6.514 | 0.5104 | Yes | ||
| 10 | GUK1 | 20432 | 179 | 6.377 | 0.5583 | Yes | ||
| 11 | ADSL | 4358 | 181 | 6.342 | 0.6066 | Yes | ||
| 12 | PAICS | 16820 | 226 | 5.909 | 0.6493 | Yes | ||
| 13 | NME6 | 3139 19297 | 352 | 5.107 | 0.6815 | Yes | ||
| 14 | RRM1 | 18163 | 391 | 4.897 | 0.7168 | Yes | ||
| 15 | DHODH | 7152 | 466 | 4.573 | 0.7477 | Yes | ||
| 16 | GMPS | 15578 | 598 | 4.048 | 0.7715 | Yes | ||
| 17 | GART | 22543 1754 | 706 | 3.684 | 0.7938 | Yes | ||
| 18 | PRPS1 | 24233 | 811 | 3.405 | 0.8142 | Yes | ||
| 19 | RRM2 | 5401 5400 | 1481 | 2.084 | 0.7941 | No | ||
| 20 | IMPDH1 | 17197 1131 | 1971 | 1.436 | 0.7787 | No | ||
| 21 | AK3L1 | 8564 | 4177 | 0.166 | 0.6613 | No | ||
| 22 | AK5 | 6042 | 4178 | 0.166 | 0.6626 | No | ||
| 23 | RRM2B | 6902 6903 11801 | 6928 | 0.036 | 0.5150 | No | ||
| 24 | PURA | 9670 | 10677 | -0.015 | 0.3134 | No | ||
| 25 | AK1 | 4363 | 12129 | -0.039 | 0.2356 | No | ||
| 26 | PRPSAP2 | 10013 1317 | 12788 | -0.055 | 0.2006 | No | ||
| 27 | NME7 | 926 4101 14070 3986 3946 931 | 13867 | -0.102 | 0.1434 | No | ||
| 28 | PRPSAP1 | 20141 | 14967 | -0.229 | 0.0860 | No | ||
| 29 | KIF13B | 21982 21983 | 15269 | -0.301 | 0.0721 | No | ||
| 30 | CTPS2 | 12060 2571 | 16346 | -0.998 | 0.0218 | No | ||
| 31 | AK2 | 8563 2479 16073 | 16931 | -1.712 | 0.0034 | No | ||
| 32 | NME3 | 23349 | 18290 | -5.314 | -0.0291 | No | ||
| 33 | ADSSL1 | 21136 2087 | 18411 | -6.116 | 0.0110 | No |
